No Influence of Type 2 Diabetes on Chronic Inflammation and Oxidative Stress in Obese Patients

  • Adriana Florinela CĂTOI Department of Physiology, Faculty of Medicine, “Iuliu Hațieganu” University of Medicine and Pharmacy“Iuliu Hațieganu” Cluj-Napoca, RO-400012, Cluj-Napoca (RO)
  • Alina Elena PÂRVU Department Pathophysiology, Faculty of Medicine, “Iuliu Hațieganu” University of Medicine and Pharmacy Cluj-Napoca (RO)
  • Adriana MUREȘAN Department of Physiology, Faculty of Medicine, “Iuliu Hațieganu” University of Medicine and Pharmacy“Iuliu Hațieganu” Cluj-Napoca, RO-400012, Cluj-Napoca (RO)
  • Cristina BIDIAN Department of Physiology, Faculty of Medicine, “Iuliu Hațieganu” University of Medicine and Pharmacy“Iuliu Hațieganu” Cluj-Napoca, RO-400012, Cluj-Napoca (RO)
  • Cornel CĂTOI Department of Exact Sciences, Horticulture Faculty, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, RO-400372 Cluj-Napoca (RO)
  • Ioana Delia POP Department of Exact Sciences, Horticulture Faculty, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, RO-400372 Cluj-Napoca (RO)
Keywords: chronic inflammation; obesity; oxidative stress; type 2 diabetes mellitus

Abstract

Obesity per se carries the features of chronic inflammation and oxidative stress that interrelate in a complex network and exert an important role in the onset of several complications such as type 2 diabetes, atherosclerosis and cardiovascular events. On the other hand, it seems that hyperglycemia per se as well as insulin resistance (independent of hyperglycemia), both induce increased oxidative stress. The aim of our study was to analyze proinflammatory and oxidative stress markers in obese patients with and without type 2 diabetes and to verify the hypothesis that type 2 diabetes associated with obesity would promote a higher chronic inflammation and oxidative stress state as compared to obesity alone. We found no differences between the two groups of patients regarding chronic inflammation and oxidative stress markers. Therefore we may conclude that there is no influence of type 2 diabetes on chronic inflammation and oxidative stress in obese patients.

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Published
2014-03-12
How to Cite
CĂTOI, A. F., PÂRVU, A. E., MUREȘAN, A., BIDIAN, C., CĂTOI, C., & POP, I. D. (2014). No Influence of Type 2 Diabetes on Chronic Inflammation and Oxidative Stress in Obese Patients. Notulae Scientia Biologicae, 6(1), 14-19. https://doi.org/10.15835/nsb619249
Section
Research articles
CITATION
DOI: 10.15835/nsb619249