Genetic Analysis of ABO and Rh Blood Groups in Backward Caste Population of Uttar Pradesh, India

  • Vandana RAI Department of Biotechnology, VBS Purvanchal University, Jaunpur (UP) 222001
  • Pradeep KUMAR Department of Biotechnology, VBS Purvanchal University, Jaunpur (UP) 222001

Abstract

A series of glycoproteins and glycolipids on red blood cell surface constitute blood group antigens. These are AB, A, B and O in ABO blood group system and Rh in rhesus blood group system. A total of 1065 unrelated Backward Caste (OBC) individuals from Uttar Pradesh were studied for the phenotype and allele frequency distribution of ABO and Rh (D) blood groups. Total 1065 samples analyzed, phenotype B blood type has the highest frequency 36.81% (n=392), followed by O (32.68%; n=348), A (23.66%; n=252) and AB (6.85%; n=73). The overall phenotypic frequencies of ABO blood groups were B>O>A>AB. The allelic frequencies of O, A, and B alleles were 0.5819, 0.1674 and 0.2506 respectively. Out of total 1065 samples, 1018 (95.59%) samples were Rh-positive and 47 (4.41%) were Rh-negative. Phenotypic frequency of Rh-negative in Koari, Yadav, Kurmi and Maurya samples were 0.99%, 4%, 1.4% and 7.6% respectively.

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Author Biographies

Vandana RAI, Department of Biotechnology, VBS Purvanchal University, Jaunpur (UP) 222001
Biotechnology Associate Professor
Pradeep KUMAR, Department of Biotechnology, VBS Purvanchal University, Jaunpur (UP) 222001
Biotechnology Senior Lecturer
Published
2011-08-25
How to Cite
RAI, V., & KUMAR, P. (2011). Genetic Analysis of ABO and Rh Blood Groups in Backward Caste Population of Uttar Pradesh, India. Notulae Scientia Biologicae, 3(3), 07-14. https://doi.org/10.15835/nsb336073
Section
Medicine; Hematology; Research Articles