Bioactivity of Hertia maroccana and Teucrium malenconianum: antioxidant, antibacterial, and anti-hyperlipidemic effects

Authors

  • Hamza ELBOUNY University Moulay Ismail of Meknes, Faculty of Sciences and Technology, Department of Biology, Laboratory of Biochemistry, Errachidia (MA)
  • Rania BENJAMAA Hassan First University of Settat, Faculty of Sciences and Technologies, Laboratory of Biochemistry, Neurosciences, Natural Resources and Environment, 577, Settat (MA)
  • Brahim OUAHZIZI University Moulay Ismail of Meknes, Faculty of Sciences and Technology, Department of Biology, Laboratory of Biochemistry, Errachidia (MA)
  • Amine AZZANE Team of Ethnopharmacology and Pharmacognosy, Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes, BP 509, Boutalamine, Errachidia, 52000 (MA)
  • Abdelmonaim HOMRANI BAKALI Regional Centre of Agricultural Research of Tangier, National Institute of Agricultural Research, Avenue Ennasr, PO Box 415 Rabat Principale, 10090 Rabat (MA)
  • Mohamed BAMMOU Moulay Ismail University of Meknes, Faculty of Sciences & Techniques, Laboratory of Bioactives, Health, and Environment, Errachidia (MA)
  • Khalid SELLAM University Moulay Ismail of Meknes, Faculty of Sciences and Technology, Department of Biology, Laboratory of Biochemistry, Errachidia; Moulay Ismail University of Meknes, Faculty of Sciences & Techniques, Laboratory of Bioactives, Health, and Environment, Errachidia (MA)
  • Chakib ALEM University Moulay Ismail of Meknes, Faculty of Sciences and Technology, Department of Biology, Laboratory of Biochemistry, Errachidia (MA)

DOI:

https://doi.org/10.55779/nsb16412095

Keywords:

antibacterial, anti-hyperlipidemic, antioxidant effect, Hertia maroccana, Teucrium malenconianum

Abstract

The main goal of this study was to conduct a phytochemical investigation on the hydro-ethanolic extracts of Hertia maroccana Batt. and Teucrium malenconianum Maire. and to evaluate their antioxidant, antibacterial, and anti-hyperlipidemic activities. The phytochemical study was carried out using chemical screening tests and the antioxidant potential was assessed using in vitro methods. Moreover, agar well diffusion method was used to determine the antimicrobial properties against Staphylococcus aureus and Escherichia coli. In addition, triton-induced acute hyperlipidemia model was used to evaluate the anti-hyperlipidemic activity. The findings revealed that H. maroccana and T. malenconianum extracts contain various metabolites (such as proteins, terpenoids, cardiac glycosides, phenols, flavonoids, tannins, etc.), significant amounts of phenolic compounds (50.33 and 49.94 mg GAE/gE, respectively), and exhibit notable antioxidant properties (DPPH IC50: 1.18 and 0.97 mg/mL, respectively; ABTS IC50: 0.27 and 0.23 mg/mL, respectively; FRAP value: 0.65 and 0.7 Fe2+E mM, respectively). Moreover, we found that H. maroccana exerted an important antibacterial effect against Staphylococcus aureus (MIC = 0.39 mg/mL and MBC = 6.25 mg/mL). Additionally, T. malenconianum induced significant anti-hyperlipidemic activity. In conclusion, that H. maroccana represents a promising source of antibacterial agents whereas, T. malenconianum shows potential for managing hyperlipidemia.

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References

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Published

2024-12-19

How to Cite

ELBOUNY, H., BENJAMAA, R., OUAHZIZI, B., AZZANE, A., HOMRANI BAKALI, A., BAMMOU, M., SELLAM, K., & ALEM, C. (2024). Bioactivity of Hertia maroccana and Teucrium malenconianum: antioxidant, antibacterial, and anti-hyperlipidemic effects. Notulae Scientia Biologicae, 16(4), 12095. https://doi.org/10.55779/nsb16412095

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Research articles
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DOI: 10.55779/nsb16412095

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