Litsea glutinosa (Lauraceae): Evaluation of its Foliar Phytochemical Constituents for Antimicrobial Activity

  • Mutyala Naidu LAGUDU Adikavi Nannaya University, Department of Botany, Rajamahendravaram-533296, Andhra Pradesh
  • Aniel Kumar OWK Andhra University, Department of Botany, Visakhapatnam-530003, Andhra Pradesh
Keywords: extract; Litsea glutinosa; microorganism; pathogen; phytochemical

Abstract

The phytochemical investigation of the leaves of Litsea glutinosa revealed the presence of secondary metabolites like alkaloids, anthraquinones, cardiac glycosides, flavonoids, glycosides, phenols, saponins, steroids, tannins, terpenoids, volatile compounds, amino acids and carbohiydrates. The antimicrobial activity and minimum inhibition concentration values were determined for these phytochemical constituents as crude extracts using the agar well diffusion and two-fold serial dilution methods. The results indicated that Bacillus subtilis was the most susceptible bacterium with high inhibition zones for the methanol and chloroform extracts of 31 mm and 26 mm, respectively. The MIC values indicated that extracts possess good antimicrobial activity with significant MIC value against Enterococcus faecalis, Pseudomonas aeruginosa and Staphylococcus pneumoniae at 31.2 µg/ml concentrations. The extracts showed marked antimicrobial activity against both bacteria and fungi. Among the bacterial strains, gram-positive bacteria were more susceptible than the gram-negative. All the 13 microorganisms tested showed dose dependent susceptibility towards the phytochemicals present in the foliar extracts. The study suggests that Litsea glutinosa leaves possess potent antimicrobial activity and can be a good source for the development of new antibiotics.

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Author Biography

Mutyala Naidu LAGUDU, Adikavi Nannaya University, Department of Botany, Rajamahendravaram-533296, Andhra Pradesh
biotechnology

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Published
2018-03-27
How to Cite
LAGUDU, M. N., & OWK, A. K. (2018). Litsea glutinosa (Lauraceae): Evaluation of its Foliar Phytochemical Constituents for Antimicrobial Activity. Notulae Scientia Biologicae, 10(1), 21-25. https://doi.org/10.15835/nsb10110180
Section
Research articles